Since early collaborations with Greenpeace and Amnesty International, the band have consistently thrown a spotlight on the work of campaign groups trying to make the world a better place.
From the ONE campaign to the Chernobyl Childrens Project, from amplifying freedom in Burma to supporting communities devastated by Hurricane Katrina, U2 have worked with many great causes and activist communities.
Find out more by selecting any one organisation below.
1. THE ANGIOGENESIS FOUNDATION
'Imagine that one medical advancement held the promise to conquer cancer. Now imagine that same advance has the potential to also end more than 70 of life's most threatening conditions, affecting one billion people. This is the promise of angiogenesis, the first medical revolution of the 21st century.' Dr. William Li.
2. AMNESTY INTERNATIONAL
Amnesty International is a global movement campaigning for human rights for all. Amnesty supporters are outraged by human rights abuses but inspired by hope for a better world. They work to improve human rights through campaigning and international solidarity.
3. CHERNOBYL CHILDREN'S PROJECT
Established in 1991, the Chernobyl Children's Project aims to alleviate the suffering and offer hope to those affected by the Chernobyl nuclear explosion - the children of Belarus, Western Russia and the Ukraine.
4. FREE BURMA
Aung San Suu Kyi, pro-democracy leader and Nobel Peace laureate, has long symbolised the struggle of Burma's people to be free. Her message is a simple one - that only by fighting fear can you truly be free. U2's Grammy winning song Walk On is dedicated to Aung San Suu Kyi.
The core principle of Greenpeace, founded in 1971, is to prevent harm to the environment using the concept of non-violent direct action.
Mencap works with people with a learning disability to change laws, challenge prejudice and support them to live their lives as they choose.
7. MUSIC RISING
Music Rising was launched by The Edge, Bob Ezrin and Henry Juszkiewicz to rescue the musical culture of the Central Gulf region of the United States from the destruction caused by the catastrophic hurricanes of the summer of 2005 by replacing musical instruments lost or destroyed in the deluge.
ONE is a campaign and advocacy organization backed by more than 2 million people who are committed to the fight against extreme poverty and preventable disease, particularly in Africa. At ONE, we believe the fight against poverty is not about charity, but about justice and equality.
(RED) is a brand designed to engage business and consumer power to help eliminate AIDS in Africa. (RED) works with iconic brands to make unique (RED) branded products from which these companies direct up to 50% of gross profits to the Global Fund. All of this money is invested in HIV/AIDS programs in Africa.